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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKC
All Species:
32.73
Human Site:
T145
Identified Species:
55.38
UniProt:
Q9UQB9
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQB9
NP_001015878.1
309
35591
T145
L
D
E
Q
R
T
A
T
I
I
E
E
L
A
D
Chimpanzee
Pan troglodytes
XP_001142357
309
35587
T145
L
D
E
Q
R
T
A
T
I
I
E
E
L
A
D
Rhesus Macaque
Macaca mulatta
XP_001098364
471
52859
T307
L
D
E
Q
R
A
A
T
I
I
E
E
L
A
D
Dog
Lupus familis
XP_849906
346
39574
T179
F
D
E
Q
R
T
A
T
I
M
E
E
L
A
D
Cat
Felis silvestris
Mouse
Mus musculus
O88445
282
32888
C130
L
S
D
A
L
T
Y
C
H
E
K
K
V
I
H
Rat
Rattus norvegicus
O55099
343
39216
T182
F
D
E
Q
R
T
A
T
I
M
E
E
L
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
T134
F
D
E
Q
R
T
A
T
Y
I
T
E
L
A
D
Chicken
Gallus gallus
XP_425725
409
46456
T249
F
D
E
Q
R
T
A
T
Y
I
T
E
L
A
D
Frog
Xenopus laevis
Q6GPL3
368
41997
T202
F
D
E
Q
R
S
A
T
F
M
E
E
L
A
D
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
T155
F
D
D
Q
R
T
A
T
Y
M
E
E
V
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
S155
H
R
F
D
E
P
R
S
A
K
Y
T
Y
Q
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01427
305
34731
K132
F
S
E
P
T
A
A
K
Y
M
Y
E
I
A
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q683C9
282
32738
L130
V
A
S
L
A
R
A
L
I
Y
C
H
G
K
H
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
D206
F
N
D
I
L
A
S
D
Y
I
Y
Q
I
A
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
63.4
70.5
N.A.
72.4
67.3
N.A.
64.7
52.3
58.1
65.3
N.A.
43.1
N.A.
54.6
N.A.
Protein Similarity:
100
100
64.7
78.9
N.A.
82.5
79.3
N.A.
78.3
62.3
71.1
78.7
N.A.
62.6
N.A.
68.9
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
13.3
80
N.A.
80
80
73.3
60
N.A.
0
N.A.
33.3
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
40
93.3
N.A.
80
80
86.6
86.6
N.A.
6.6
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.3
38.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.8
55.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
22
79
0
8
0
0
0
0
65
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
0
65
22
8
0
0
0
8
0
0
0
0
0
0
72
% D
% Glu:
0
0
65
0
8
0
0
0
0
8
50
72
0
0
0
% E
% Phe:
58
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
8
0
0
0
0
0
0
0
8
0
0
8
0
0
15
% H
% Ile:
0
0
0
8
0
0
0
0
43
43
0
0
15
8
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
8
8
8
0
8
0
% K
% Leu:
29
0
0
8
15
0
0
8
0
0
0
0
58
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
36
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
65
0
0
0
0
0
0
0
8
0
8
0
% Q
% Arg:
0
8
0
0
65
8
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
15
8
0
0
8
8
8
0
0
0
0
0
15
0
% S
% Thr:
0
0
0
0
8
58
0
65
0
0
15
8
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
36
8
22
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _